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Updated: Jun 22, 2026

Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development
Published on: April 15, 2013
Trans isomeric and LCPUFA are inversely correlated in erythrocyte membrane lipids at mid-gestation
Tamás Marosvölgyi1, Cristina Campoy, Berthold Koletzko
1Department of Paediatrics, University of Pécs, Pécs, Hungary.
Abstract:
Fatty acid composition of erythrocyte phosphatidylcholines was determined by high-resolution capillary gas chromatography in Spanish (n = 120), German (n = 78) and Hungarian (n = 43) expectant women at the 20th week of gestation. The sum of trans isomeric fatty acids was significantly (p < 0.05) lower in Hungarian (0.68 [0.43]% wt/wt, median [IQR]) than in Spanish (0.82 [0.53]) expectant women. There were no significant correlations between the sum of trans isomers and linoleic acid or alpha-linolenic acid in either of the three groups. In contrast, there were significant inverse correlations between the sum of trans fatty acids and arachidonic acid and docosahexaenoic acid in all the three groups. These data raise the possibility that maternal trans isomeric fatty acid status may be inversely associated to the essential fatty acid status of the foetus.
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