Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 22, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

[Not Available].

S Pandav1, W H Morgan, R Townsend

  • 1Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, Perth, Western Australia 6009, Australia.

The Open Ophthalmology Journal
|June 24, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

The Availability Heuristic01:08

The Availability Heuristic

A heuristic is a general problem-solving framework (Tversky & Kahneman, 1974). You can think of these as mental shortcuts that are used to solve problems. Different types of heuristics are used in different types of situations, and the impulse to use a heuristic occurs when one of five conditions is met (Pratkanis, 1989):

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Calculation of vessel pulse wave velocities in retinal vein segments within the optic disc centre.

Scientific reports·2024
Same author

Mating system induced lags in rates of range expansion for different simulated mating systems and dispersal strategies: a modelling study.

Oecologia·2024
Same author

[Safety and efficacy of the early administration of levosimendan in patients with acute non-ST-segment elevation myocardial infarction and elevated NT-proBNP levels: An Early Management Strategy of Acute Heart Failure (EMS-AHF)].

Zhonghua nei ke za zhi·2023
Same author

Correlation between retinal vein pulse amplitude, estimated intracranial pressure, and postural change.

NPJ microgravity·2023
Same author

Principles and philosophies for speech and language therapists working with people with primary progressive aphasia: an international expert consensus.

Disability and rehabilitation·2022
Same author

Zero retinal vein pulsation amplitude extrapolated model in non-invasive intracranial pressure estimation.

Scientific reports·2022
Same journal

Polymorphisms of Aldose Reductase (ALR2) Regulatory Gene are Risk Factors for Diabetic Retinopathy in Type-2 Diabetes Mellitus Patients in Bali, Indonesia.

The open ophthalmology journal·2018
Same journal

Maximising Refractive Outcomes with an Extended Depth of Focus IOL.

The open ophthalmology journal·2018
Same journal

Refractive Error among Male Primary School Students in Jazan, Saudi Arabia: Prevalence and Associated Factors.

The open ophthalmology journal·2018
Same journal

Outcomes of Wavefront-Optimized Laser-Assisted <i>In-Situ</i> Keratomileusis and Photorefractive Keratectomy for correction of Myopia and Myopic Astigmatism over One Year Follow-Up.

The open ophthalmology journal·2018
Same journal

Clinical Characteristics, Treatment Outcomes and Predictive Factors in Optic Neuritis.

The open ophthalmology journal·2018
Same journal

A New User-Friendly and Affordable Method in Descemet Stripping Endothelial Keratoplasty.

The open ophthalmology journal·2018
See all related articles

The Heidelberg Retinal Flowmeter (HRF) cannot measure choroidal blood flow in pig eyes. A conventional Laser Doppler Perfusion Monitor (LDPM) showed a strong correlation, indicating the HRF

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Physiology

Background:

  • Choroidal blood flow is crucial for retinal health.
  • Accurate measurement of choroidal hemodynamics is essential for understanding ocular diseases.
  • Existing technologies for blood flow measurement may have limitations in specific ocular tissues.

Purpose of the Study:

  • To evaluate the capability of the Heidelberg Retinal Flowmeter (HRF) to measure choroidal blood flow.
  • To compare HRF measurements with a conventional Laser Doppler Perfusion Monitor (LDPM).
  • To assess HRF performance in both in vitro and in vivo porcine eye models.

Main Methods:

  • Utilized an HRF and LDPM to measure choroidal blood flow in isolated pig eyes under controlled perfusion rates.
Keywords:
Blood flowchoroidheidelberg retinal flowmeterhrflaser doppler flowmetry

Related Experiment Videos

Last Updated: Jun 22, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
12:33

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

  • Compared HRF-derived flow maps with simultaneous LDPM measurements.
  • Acquired in vivo HRF flow maps at varying focal planes through the porcine retina and choroid.

    • Main Results:

    • The HRF demonstrated a poor correlation between measured flow and actual perfusion rates in isolated pig eyes.
    • The LDPM exhibited a strong linear relationship with perfusion flow, validating its accuracy.
    • Choroidal vessels were not visualized in HRF flow maps, irrespective of focal plane settings, in both in vitro and in vivo experiments.

    Conclusions:

    • The Heidelberg Retinal Flowmeter is not suitable for measuring choroidal blood flow in porcine eyes.
    • The limitations are not attributed to laser penetration or red blood cell velocity ranges.
    • Conventional LDPM remains a reliable method for assessing choroidal blood flow in this model.