Related Experiment Video
Updated: Jun 22, 2026
26:41
Perspectives on Neuroscience
Published on: July 31, 2007
Psychiatric neurosurgery 2009: review and perspective
Cynthia N Read1, Benjamin D Greenberg
1Brown University/Butler Hospital, Providence, Rhode Island 02906, USA.
Seminars in Neurology
|June 25, 2009
Summary
Deep brain stimulation (DBS) and lesion procedures offer hope for severe psychiatric disorders like OCD and MDD. Careful patient selection and long-term care are crucial for successful neurosurgical treatment outcomes.
Area of Science:
- Neurosurgery
- Psychiatry
- Neurology
Background:
- Pharmacological and behavioral treatments are insufficient for some patients with severe psychiatric disorders.
- Modern neurosurgical interventions are emerging as potential therapeutic options.
Observation:
- Deep brain stimulation (DBS) and lesion procedures show therapeutic promise, particularly for obsessive-compulsive disorder (OCD) and major depressive disorder (MDD).
- These interventions require careful consideration regarding patient selection and long-term management.
Findings:
- Psychiatric neurosurgery is most effective within a multimodal treatment plan.
- Dedicated interdisciplinary teams are essential for successful implementation.
- Both DBS and lesion procedures present distinct patterns of potential clinical benefits and burdens.
Implications:
- Neurosurgical treatments for psychiatric conditions necessitate a cautious approach with a commitment to ongoing patient care.
- Further research is needed to optimize patient selection criteria and long-term management strategies for DBS and lesion procedures.
- These advanced treatments highlight the evolving landscape of psychiatric care for treatment-resistant conditions.
