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Polycystic ovaries and infertility: Our experience
Lavanya Rajashekar1, Deepika Krishna, Madhuri Patil
1Dr. Patil's Fertility and Endoscopy Clinic, No 1, Uma Admirality, First Floor, Bannerghatta Road, Bangalore, Karnataka-560 029, India.
Journal of Human Reproductive Sciences
|June 30, 2009
Summary
Polycystic ovary syndrome (PCOS) affects 15-20% of women and is a common cause of infertility. This study found an overall pregnancy rate of 48.40% in PCOS patients undergoing various fertility treatments.
Area of Science:
- Reproductive Endocrinology
- Gynecology
Background:
- Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting 15-20% of women of reproductive age.
- It is a significant contributor to female infertility, with unknown etiology and challenging treatment.
Purpose of the Study:
- To determine the incidence, treatment approaches, and outcomes for patients diagnosed with PCOS.
- To analyze the effectiveness of different fertility treatments in PCOS patients.
Main Methods:
- Retrospective analysis of 914 PCOS patients from June 2003 to February 2008.
- Evaluation of hormonal disturbances and treatment responses in 814 patients seeking treatment.
Main Results:
- PCOS was identified in 46.50% of 2270 infertility patients.
- An overall pregnancy rate of 48.40% was achieved.
- Pregnancy rates varied by treatment: timed intercourse (44.77%), intrauterine insemination (17.09%), in vitro fertilization (29.82%), and frozen embryo transfer (22.22%).
- Most pregnancies (85.29%) occurred within the first three treatment cycles.
- Complications included an abortion rate of 19.01%, ectopic pregnancy incidence of 5.47%, and ovarian hyperstimulation syndrome.
Conclusions:
- PCOS symptoms can be effectively managed with accurate diagnosis and appropriate treatment.
- Balancing ovulation induction protocols and treatment modalities is crucial for optimizing reproductive outcomes in PCOS patients.
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