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Related Concept Videos

Distributions to Estimate Population Parameter01:26

Distributions to Estimate Population Parameter

The accurate values of population parameters such as population proportion, population mean, and population standard deviation (or variance) are usually unknown. These are fixed values that can only be estimated from the data collected from the samples. The estimates of each of these parameters are sample proportion, the sample mean, and sample standard deviation (or variance). To obtain the values of these sample statistics, data are required that have particular distribution and central...
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least squares (OLS)...
Estimating Population Standard Deviation01:26

Estimating Population Standard Deviation

When the population standard deviation is unknown and the sample size is large, the sample standard deviation s is commonly used as a point estimate of σ. However, it can sometimes under or overestimate the population standard deviation. To overcome this drawback, confidence intervals are determined to estimate population parameters and eliminate any calculation bias accurately. However, this only applies to random samples from normally distributed populations. Knowing the sample mean and...
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
Estimating Population Mean with Unknown Standard Deviation01:22

Estimating Population Mean with Unknown Standard Deviation

In practice, we rarely know the population standard deviation. In the past, when the sample size was large, this did not present a problem to statisticians. They used the sample standard deviation s as an estimate for σ and proceeded as before to calculate a confidence interval with close enough results. However, statisticians ran into problems when the sample size was small. A small sample size caused inaccuracies in the confidence interval.
William S. Gosset (1876–1937) of the Guinness...

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Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
04:35

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Published on: July 3, 2020

Model-based multiplicity estimation of population size.

Eugene M Laska1, Morris Meisner, Joseph Wanderling

  • 1Statistics and Services Research Division, The Nathan S. Kline Institute for Psychiatric Research, New York University School of Medicine, Orangeburg, NY 10962, USA. laska@nki.rfmh.org

Statistics in Medicine
|July 3, 2009
PubMed
Summary
This summary is machine-generated.

This study introduces a new survey method for estimating population size (N) using purposively selected samples. This model-based approach can yield more precise estimates than traditional random sampling when the sample is typical.

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Area of Science:

  • Statistics
  • Survey Methodology
  • Epidemiology

Background:

  • Estimating population size (N) is crucial in various fields.
  • Traditional methods rely on probability sampling, which can be resource-intensive.
  • Purposive sampling offers an alternative for selecting 'typical' samples.

Purpose of the Study:

  • To develop and evaluate a model-based estimator for population size (N).
  • To compare the efficiency of purposive sampling with traditional random sampling.
  • To investigate the conditions under which model-based inference is valid.

Main Methods:

  • A novel estimator using participant data (u, j) on selection units (w of K).
  • Purposive selection of survey units to maximize sample typicality.
  • Model-based analysis for statistical inference.

Main Results:

  • Maximum Likelihood (ML) estimators for N and E(J) are unbiased for typical samples.
  • Model-based variance can be smaller than random sampling variance under specific conditions.
  • The study highlights the importance of sample selection for model validity.

Conclusions:

  • Purposive sampling with a model-based approach offers a potentially more efficient method for estimating population size (N).
  • Careful selection of 'typical' samples is critical for the validity and precision of the estimator.
  • Further research is needed to develop methods for assessing sample typicality.