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Updated: Jun 21, 2026

Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
Spontaneous hepatic hemorrhage secondary to prolonged use of oral contraceptives
Reema Jaffar1, Liberto Pechet, Giles Francis Whalen
1Department of Anatomical Pathology, UMass Memorial Medical Center, Biotech Three One Innovation Drive, Worcester, MA 01605, USA. Reema.Jaffar@Umassmemorial.org
Abstract:
Oral contraceptive pills (OCP) are the most commonly used form of contraception throughout the United States of America. The prolonged usage of oral contraceptives leads to a variety of complications, ranging from subclinical modifications of liver function tests to the development of benign and malignant tumors of the liver. Spontaneous hepatic hemorrhage secondary to oral contraceptive use was only reported once in the early 1980s. We report a case of spontaneous hepatic hemorrhage secondary to prolonged ingestion of combined OCPs followed by multiple pulmonary emboli without underlying thrombophilia.
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