Related Experiment Video

Updated: Jun 21, 2026

Isolation of Salivary Epithelial Cells from Human Salivary Glands for In Vitro Growth as Salispheres or Monolayers
08:03

Isolation of Salivary Epithelial Cells from Human Salivary Glands for In Vitro Growth as Salispheres or Monolayers

Published on: July 15, 2019

Non-HIV viral infections of the salivary glands

Andrea Schreiber1, Gabriel Hershman

  • 1Department of Oral and Maxillofacial Surgery, New York University College of Dentistry, New York, NY, USA. andrea.schreiber@nyu.edu

Oral and Maxillofacial Surgery Clinics of North America
|July 18, 2009
PubMed

Insights

Mumps remains a significant viral salivary gland infection, with outbreaks occurring despite widespread vaccination. Epidemiologic studies are crucial for understanding causes and developing better vaccination strategies for eradication.

Area of Science:

  • Virology
  • Epidemiology
  • Immunology

Background:

  • Mumps is historically the most significant non-HIV viral infection affecting salivary glands.
  • Despite global mumps vaccination efforts, sporadic outbreaks persist, highlighting ongoing challenges.

Purpose of the Study:

  • To underscore the importance of epidemiologic studies in understanding mumps outbreak etiology.
  • To explore how integrated scientific advances can lead to mumps eradication.

Main Methods:

  • Review of historical and current epidemiologic data on mumps.
  • Integration of immunological and virological findings.
  • Analysis of DNA/RNA testing advancements.

Main Results:

  • Mumps virus continues to be a primary viral pathogen of salivary glands.
  • Outbreaks indicate limitations in current vaccination strategies or implementation.
  • Epidemiologic data provides critical insights into disease transmission patterns.

Conclusions:

  • Continued epidemiologic surveillance is essential for mumps control.
  • Advancements in immunology, virology, and molecular diagnostics are key to improving vaccination efficacy.
  • The ultimate goal is the complete eradication of mumps through enhanced vaccination regimens.

More Related Videos

Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction07:44

Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction

Published on: April 24, 2016

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients05:26

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Related Concept Videos

Herpes01:28

Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
Salivary Glands and Saliva01:23

Salivary Glands and Saliva

The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...