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Microalbuminuria prevalence study in hypertensive patients with type 2 diabetes in Pakistan
Muhammad Yakoob Ahmadani1, Asher Fawwad, Abdul Basit
1Department of Medicine, Baqai Medical University, Karachi, Pakistan.
Background:
Microalbuminuria is a renal marker of general vascular endothelial damage and early atherosclerosis with adverse prognostic implications. It is associated with diabetes, insulin resistance, central adiposity and hypertension.
Objective:
The Microalbuminuria Prevalence Study (MAPS) aimed to assess the prevalence of microalbuminuria in consecutively-screened hypertensive adult patients with type 2 diabetes mellitus in 103 centres of ten Asian countries.
Design:
Cross-sectional clinic-based epidemiological study.
Methods:
This is the sub-analysis of data collected from patients attending the OPD of Baqai Institute of Diabetology and Endocrinology in Pakistan. Patients attended one study visit with no follow-up. Patients with bacteriuria and haematuria were excluded.
Results:
A total of 99 subjects were studied out of which 56.3% were females. Mean age was 49.9 +/- 10.8 years. The prevalence of macroalbuminuria and microalbuminuria was 9.09% and 24.2% respectively.
Conclusion:
In Pakistan the prevalence of diabetic kidney disease was high in diabetic hypertensive subjects which is alarming and indicates an impending pandemic of diabetic renal and cardiovascular disease in the region.
Insights
Microalbuminuria, a marker of vascular damage, affects 24.2% of hypertensive adults with type 2 diabetes in Pakistan. This high prevalence of diabetic kidney disease signals a growing health crisis.
Area of Science:
- Nephrology
- Endocrinology
- Cardiovascular Medicine
Background:
- Microalbuminuria indicates vascular endothelial damage and early atherosclerosis.
- It is linked to diabetes, insulin resistance, central adiposity, and hypertension.
- Early detection is crucial for managing adverse prognostic implications.
Purpose of the Study:
- To determine the prevalence of microalbuminuria in hypertensive patients with type 2 diabetes in Pakistan.
- This study is a sub-analysis of the Microalbuminuria Prevalence Study (MAPS) in Asia.
- To highlight the urgent need for intervention in the region.
Main Methods:
- Cross-sectional, clinic-based epidemiological study.
- Data collected from hypertensive patients with type 2 diabetes at Baqai Institute of Diabetology and Endocrinology, Pakistan.
- Exclusion criteria included bacteriuria and haematuria.
Main Results:
- A total of 99 subjects were analyzed (56.3% female).
- The prevalence of microalbuminuria was 24.2%.
- Macroalbuminuria prevalence was 9.09%.
Conclusions:
- Diabetic kidney disease is highly prevalent in hypertensive diabetic subjects in Pakistan.
- This indicates a significant and alarming public health concern.
- There is an impending pandemic of diabetic renal and cardiovascular disease in the region.
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