Microalbuminuria prevalence study in hypertensive patients with type 2 diabetes in Pakistan

Muhammad Yakoob Ahmadani1, Asher Fawwad, Abdul Basit

  • 1Department of Medicine, Baqai Medical University, Karachi, Pakistan.

Abstract

Insights

Microalbuminuria, a marker of vascular damage, affects 24.2% of hypertensive adults with type 2 diabetes in Pakistan. This high prevalence of diabetic kidney disease signals a growing health crisis.

Area of Science:

  • Nephrology
  • Endocrinology
  • Cardiovascular Medicine

Background:

  • Microalbuminuria indicates vascular endothelial damage and early atherosclerosis.
  • It is linked to diabetes, insulin resistance, central adiposity, and hypertension.
  • Early detection is crucial for managing adverse prognostic implications.

Purpose of the Study:

  • To determine the prevalence of microalbuminuria in hypertensive patients with type 2 diabetes in Pakistan.
  • This study is a sub-analysis of the Microalbuminuria Prevalence Study (MAPS) in Asia.
  • To highlight the urgent need for intervention in the region.

Main Methods:

  • Cross-sectional, clinic-based epidemiological study.
  • Data collected from hypertensive patients with type 2 diabetes at Baqai Institute of Diabetology and Endocrinology, Pakistan.
  • Exclusion criteria included bacteriuria and haematuria.

Main Results:

  • A total of 99 subjects were analyzed (56.3% female).
  • The prevalence of microalbuminuria was 24.2%.
  • Macroalbuminuria prevalence was 9.09%.

Conclusions:

  • Diabetic kidney disease is highly prevalent in hypertensive diabetic subjects in Pakistan.
  • This indicates a significant and alarming public health concern.
  • There is an impending pandemic of diabetic renal and cardiovascular disease in the region.

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