[Evidence-based anti-infective program "ABx" - Online-program for anti-infective therapy broadens functions for local...

Area of Science:

• Critical Care Medicine
• Infectious Diseases
• Clinical Pharmacy

Context:

• Evidence-based recommendations for anti-infective therapies in intensive care units (ICUs) present implementation challenges in daily clinical practice.
• Effective and timely anti-infective treatments are crucial for managing severe infections and improving patient outcomes.
• Existing guidelines often lack integration with local institutional standards and resistance patterns.

Purpose:

• To develop a web-based program supporting the implementation of evidence-based anti-infective therapies in ICUs.
• To create interdisciplinary algorithms for immediate diagnostics and initial anti-infective treatment decisions.
• To launch the "ABx local" subproject, unifying guidelines with local standards for optimized therapy selection based on resistance data.

Summary:

• A web-based anti-infective program, supported by the German Society of Anaesthesiology and Intensive Care Medicine and the Association of German Anaesthesiologists (DGAI/BDA), has been developed to address the difficulties in applying evidence-based recommendations in ICUs.
• The program features interdisciplinary algorithms for rapid diagnostics and initial anti-infective therapies.
• "ABx local," a subproject, integrates current evidence-based recommendations with local internal standards and comments on a single platform to prioritize therapy options, considering factors like resistance patterns.

Impact:

• Facilitates the practical application of evidence-based anti-infective guidelines in intensive care settings.
• Aims to improve the quality and timeliness of anti-infective treatments, potentially leading to better clinical outcomes for severe infections.
• Enhances decision-making by providing a unified platform for evidence-based recommendations and local resistance data, optimizing anti-infective therapy selection.