Related Experiment Video
Updated: Jun 21, 2026

03:59
Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy
Published on: January 10, 2019
Reoperative endoscopic sympathectomy for persistent or recurrent palmar hyperhidrosis.
Richard K Freeman1, Jaclyn M Van Woerkom, Amy Vyverberg
1Department of Thoracic and Cardiovascular Surgery, St Vincent Hospital, Indianapolis, Indiana, USA. rfreeman@corvascmds.com
The Annals of Thoracic Surgery
|July 28, 2009
Summary
Reoperative thoracoscopic sympathectomy (RS) offers comparable improvement for palmar hyperhidrosis to initial sympathectomy. However, RS involves a longer hospital stay and increased compensatory sweating, making it a viable option for persistent symptoms.
Area of Science:
- Thoracic surgery
- Neurosurgery
- Dermatology
Background:
- Sympathectomy is a treatment for severe palmar hyperhidrosis.
- Some patients experience persistent or recurrent hyperhidrosis after initial sympathectomy.
Purpose of the Study:
- To review the experience with reoperative thoracoscopic sympathectomy (RS) for palmar hyperhidrosis.
- To compare the outcomes of RS with initial thoracoscopic sympathectomy (TS).
Main Methods:
- Retrospective analysis of patients undergoing RS for palmar hyperhidrosis.
- Comparison with patients undergoing initial TS during the same period.
- Analysis of previous sympathectomy methods, operative complications, and outcomes.
Main Results:
- RS provided comparable alleviation of palmar hyperhidrosis to TS (38/40 vs. 316/321).
- RS was associated with increased pleural adhesions, need for pleural drainage, and longer hospital stay.
- Higher rates of compensatory sweating were observed in the RS group (21/40 vs. 101/321).
Conclusions:
- Reoperative thoracoscopic sympathectomy is a safe and effective option for severe palmar hyperhidrosis refractory to initial sympathectomy.
- RS yields comparable symptom improvement but with increased operative difficulty and side effects.
- Careful patient selection is essential for reoperative sympathectomy.

