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Published on: February 2, 2024
[Two diterpenoids from herbs of Huperzia serrata]
Yabin Yang1, Xueqiong Yang, Yanqun Xu
1Key laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
Objective:
To investigate the constituents from Huperzia serrata.
Method:
Two diterpenoid compounds were isolated by column chromatography with silica gel and Sephadex LH-20. The structures were elucidated by spectral analysis and X-ray crystallographic analysis.
Result:
Their structures were determined as (15R)-12, 16-epoxy-11, 14-dihydroxy-8, 11, 13-abietatrien-7-one (1) and 3beta-hydroxysandaracopimaric acid (2).
Conclusion:
Compound 1 was a new natural abietane-type diterpenoid, compound 2 was isolated from this plant for the first time.
