Related Experiment Video

Updated: Jun 21, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
06:37

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

Published on: April 4, 2025

Height and weight growth in children with vesicoureteral reflux diagnosed before one year old

Lin-shien Fu1, Yin-Tai Hong, San-Ging Shu

  • 1Department of Pediatrics, Veterans General Hospital, Taichung, Taiwan. linshienfu@yahoo.com.tw

Urology
|August 1, 2009
PubMed

Insights

Early treatment and surgical correction for pediatric vesicoureteral reflux (VUR) can improve height growth. Prompt intervention is key for better outcomes in children with VUR.

Area of Science:

  • Pediatric Nephrology
  • Growth and Development
  • Urology

Background:

  • Vesicoureteral reflux (VUR) is a common condition in infants, often diagnosed after urinary tract infections.
  • Growth parameters like height and weight are crucial indicators of health in children with VUR.
  • Treatment strategies vary, impacting long-term growth outcomes.

Purpose of the Study:

  • To evaluate the impact of different treatment strategies on height and weight growth in children diagnosed with VUR before one year of age.
  • To compare outcomes between spontaneous recovery, surgical correction, and ongoing antibiotic prophylaxis.

Main Methods:

  • Retrospective study of 108 children (79 boys, 29 girls) with VUR diagnosed before age one.
  • Follow-up ranged from 14-152 months, assessing height Z-score (HZ) and weight-for-height index (WHI).
  • Patients were categorized into spontaneous recovery, surgical correction, and non-recovered groups.

Main Results:

  • Complete recovery, regardless of method, showed a protective effect against height Z-score decrease.
  • Surgical correction was associated with higher rates of moderate/severe VUR, faster recovery, and significantly better final height Z-scores compared to antibiotic prophylaxis alone.
  • Recovered groups exhibited better annual height Z-score changes than non-recovered patients.

Conclusions:

  • Early intervention for VUR is recommended to optimize height growth.
  • Surgical correction should be considered for children with VUR who do not achieve complete recovery with prolonged antibiotic prophylaxis.
  • Monitoring growth parameters is essential for assessing the effectiveness of VUR treatment strategies.
Abstract

More Related Videos

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection06:05

Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection

Published on: October 12, 2017

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Related Concept Videos

Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
Urodynamic Studies: Uroflowmetry01:19

Urodynamic Studies: Uroflowmetry

Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
Urinary Tract Calculi V: Nursing Management01:28

Urinary Tract Calculi V: Nursing Management

AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
Ureters01:22

Ureters

The ureters are retroperitoneal tubes located on either side of the vertebral column. They are responsible for transporting urine from each kidney to the urinary bladder. These tubes have thick walls and are approximately 25-30 cm long. Their diameter is around 10 mm at the renal pelvis, gradually narrowing to 1 mm as the ureter obliquely enters the posterior bladder wall through the ureteric orifices. The shape of these orifices is slit-like, which helps to prevent urine backflow toward the...