Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurable progression of giant cell tumour of bone associated with pregnancy - A tertiary sarcoma centre analysis.

Journal of clinical orthopaedics and trauma·2024
Same author

Outcomes Following Pedestal Cup Reconstruction of (Impending) Pathological Fractures of the Acetabulum due to Metastatic Bone Disease.

Indian journal of surgical oncology·2024
Same author

An evaluation of AI generated literature reviews in musculoskeletal radiology.

The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·2024
Same author

The influence of site on the incidence and diagnosis of solitary central cartilage tumours of the femur. A 21<sup>st</sup> century perspective.

Journal of clinical orthopaedics and trauma·2022
Same author

Computer assisted tumour surgery - An insight.

Journal of orthopaedics·2020
Same author

Advances in image enhancement for sarcoma surgery.

Cancer letters·2020
Same journal

Comorbidities in Perthes' disease: a case control study using the General Practice Research database.

The Journal of bone and joint surgery. British volume·2012
Same journal

The treatment of complex tibial shaft fractures by the Ilizarov method.

The Journal of bone and joint surgery. British volume·2012
Same journal

Posterior spinal arthrodesis for adolescent idiopathic scoliosis using pedicle screw instrumentation: does a bilateral or unilateral screw technique affect surgical outcome?

The Journal of bone and joint surgery. British volume·2012
Same journal

Anterior deltoid deficiency in reverse total shoulder replacement: a biomechanical study with cadavers.

The Journal of bone and joint surgery. British volume·2012
Same journal

Long-term results of dorsal intercarpal ligament capsulodesis for the treatment of chronic scapholunate instability.

The Journal of bone and joint surgery. British volume·2012
Same journal

Medial patellofemoral ligament reconstruction for patellar instability in patients with hypermobility: a case control study.

The Journal of bone and joint surgery. British volume·2012
See all related articles

Related Experiment Video

Updated: Jun 21, 2026

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

Soft-tissue metastases: their presentation and origin.

R Abed1, R J Grimer, S R Carter

  • 1Royal Orthopaedic Hospital, Bristol Road South, Birmingham B312AP, UK.

The Journal of Bone and Joint Surgery. British Volume
|August 5, 2009
PubMed
Summary
This summary is machine-generated.

Soft-tissue metastases are rare (1.3%) but present as painful, deep lumps. Patients with these metastases often have similar clinical features to soft-tissue sarcomas, requiring specialized assessment.

More Related Videos

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
08:54

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells

Published on: May 20, 2020

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis
07:00

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis

Published on: September 26, 2016

Related Experiment Videos

Last Updated: Jun 21, 2026

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
06:53

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone

Published on: September 9, 2020

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells
08:54

Pathological Analysis of Lung Metastasis Following Lateral Tail-Vein Injection of Tumor Cells

Published on: May 20, 2020

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis
07:00

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis

Published on: September 26, 2016

Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Soft-tissue masses are frequently investigated.
  • Soft-tissue metastases are uncommon findings.

Purpose of the Study:

  • To define clinical features of patients with soft-tissue metastases.
  • To identify primary tumor sites for soft-tissue metastases.

Main Methods:

  • Retrospective database analysis of 7935 patients.
  • Clinical feature and primary tumor site identification.

Main Results:

  • 1.3% of patients had soft-tissue metastases.
  • Metastases presented as painful, deep lumps (mean 8.3 cm).
  • Common primary sites included lung, melanoma, and kidney.

Conclusions:

  • Soft-tissue metastases share clinical features with soft-tissue sarcomas.
  • Patients with suspicious soft-tissue lumps need assessment at specialized centers.