Related Experiment Video
Updated: Jun 21, 2026
09:27
Cell Sorting of Neural Stem and Progenitor Cells from the Adult Mouse Subventricular Zone and Live-imaging of their Cell Cycle Dynamics
Published on: September 14, 2015
Identifying and enumerating neural stem cells: application to aging and cancer
Loic P Deleyrolle1, Brent A Reynolds
1Department of Neurosurgery, McKnight Brain Institute, University of Florida, Gainesville, FL, USA. loic.deleyrolle@neurosurgery.ufl.edu
Progress in Brain Research
|August 8, 2009
Summary
Adult neural stem cells offer potential for repair and cell therapies. New assays help study their roles in aging and cancer.
Area of Science:
- Neuroscience
- Stem Cell Biology
Background:
- Adult central nervous system harbors neural stem cells.
- These cells hold promise for endogenous repair and cell-based therapies.
Purpose of the Study:
- Investigate neural stem cell properties.
- Explore mechanisms of neural stem cells in aging and cancer.
Main Methods:
- Neurosphere assay.
- Neural-colony forming cell assay.
Main Results:
- Established protocols enable accurate investigation of neural stem cell properties.
- Facilitated exploration of neural stem cell roles in aging and cancer.
Conclusions:
- Discovery of adult neural stem cells opens avenues for regenerative medicine.
- Experimental assays are crucial for understanding neural stem cell functions in health and disease.
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