Related Experiment Video
Updated: Jun 21, 2026
A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
A clampless and sutureless aorto-prosthetic end-to-side anastomotic device: an experimental study
Y S Alimi1, B Saint Lebes, V Garitey
1Service de chirurgie vasculaire, Centre hospitalo-universitaire Nord, Marseille, France. yves.alimi@ap-hm.fr
Objectives:
A feasibility study.
Methods:
Eight pigs (all females; mean weight: 29 kg) underwent a conventional transperitoneal aortic approach with implantation of an aorto-prosthetic end-to-side anastomosis using a Clampless device and deployment of a 5-mm polytetrafluoroethylene (PTFE) graft. After proximal ligature, a conventional end-to-end anastomosis was then performed between the graft and the left iliac artery.
Results:
The first pig died during the procedure due to graft misplacement. The seven other procedures were successful with a mean operative and anastomosis time of 101 min (range: 81-115 min) and 3.35 min (range: 2.25-4.25 min), respectively; mean blood loss was 152 ml (range: 30-235 ml). Another pig with a patent graft died at day 4 as a result of a severe unrelated pneumonopathy. The angiogram performed during the procedure and before sacrifice, at 2 (n=2), 4 (n=2) and 6 weeks (n=2), showed no graft stenosis or thrombosis. Microscopic examination revealed a tissue covering the intraluminal stent, which evolved over time, with no visible endothelial proliferation or inflammation.
Conclusion:
An aorto-prosthetic anastomosis can be performed safely and efficiently with our new clampless and sutureless device. The next step will be a laparoscopic Clampless implantation.
