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Updated: Jun 21, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Psoriasis induced or aggravated by drugs
Franco Rongioletti1, Cristina Fiorucci, Aurora Parodi
1Section of Dermatology, DISEM, University of Genoa, 16132, Genova, Italy. franco.rongioletti@unige.it
Abstract:
Drug ingestion may result in exacerbation of preexisting psoriasis, induction of psoriatic lesions on clinically uninvolved skin in patients with psoriasis, or precipitation of the disease. In view of their relationship to psoriasis, therapeutic agents may be classified as follows: (1) drugs with strong evidence for a causal relationship to psoriasis including lithium, beta blockers, and synthetic antimalarial drugs; (2) drugs with considerable number of studies but insufficient data to support induction or aggravation of the disease; (3) drugs occasionally reported to be associated with aggravation or induction. While focusing on the most common causative agents for drug induced/aggravated psoriasis, we discuss the controversies about the relationship between drugs and psoriasis and report our own experience at the Section of Dermatology, University of Genoa.
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