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Related Experiment Video

Updated: Jun 21, 2026

Transient Middle Cerebral Artery Occlusion Model of Stroke

Transient Middle Cerebral Artery Occlusion Model of Stroke

Published on: August 11, 2023

Aortogenic cerebrovascular accident.

Shin-ichi Ohki¹, Insu Kubota, Kei Aizawa

¹Division of Cardiovascular Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan.

Interactive Cardiovascular and Thoracic Surgery

|August 12, 2009

Summary

A patient with neurological symptoms had aortic mural thrombi, which were successfully removed. This surgical intervention resolved the cerebrovascular symptoms, leading to a full recovery.

Area of Science:

Cardiovascular Medicine
Neurology
Vascular Surgery

Background:

Mural thrombi in the ascending aorta can lead to embolic events, causing cerebrovascular symptoms.
Atherosclerosis is a common underlying condition contributing to aortic pathology.

Observation:

A 59-year-old male presented with neurological dysfunction attributed to a mobile mural mass in the ascending aorta.
Echocardiography and 3D CT confirmed the presence of the aortic mural mass.
No coagulopathy was identified as a contributing factor.

Findings:

Surgical removal of the aortic mural masses was performed under cardiopulmonary bypass.
Pathological examination revealed the masses to be organizing thrombi originating from an atherosclerotic aortic wall.

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Permanent Cerebral Vessel Occlusion via Double Ligature and Transection

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The patient experienced an uneventful postoperative recovery.

Implications:

Surgical resection of aortic mural thrombi is an effective treatment for preventing recurrent cerebrovascular events.
Early diagnosis and intervention can significantly improve patient outcomes in cases of aortic thrombus.
This case highlights the importance of considering aortic pathology in patients with unexplained neurological symptoms.