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Bilateral Common Carotid Artery Occlusion as an Adequate Preconditioning Stimulus to Induce Early Ischemic Tolerance to Focal Cerebral Ischemia
Published on: May 9, 2013
Conjunctival-corneal melt in association with carotid artery stenosis
Rosalind M K Stewart1, Say Aun Quah, Dan Q Nguyen
1St Paul’s Eye Unit, Royal Liverpool University Hospital, Liverpool, UK. rosalindstewart@doctors.org.uk
Purpose:
To report a case of severe conjunctival-corneal melt in association with carotid artery stenosis.
Methods:
Observational case report.
Results:
A 76-year-old man with a history of bilateral severe carotid artery occlusion and nonarteritic ischemic optic neuropathy developed a spontaneous bulbar conjunctival defect. Despite intensive lubrication, and attempts at surgical closure including an amniotic membrane patch graft, it progressed with subsequent adjacent corneal perforation. Thorough investigations revealed no underlying disease, except markedly delayed episcleral vessel filling on anterior segment fluorescein angiography.
Conclusions:
Neovascularisation is a known factor in the inhibition of ulceration. In light of the findings in this report, ocular ischemia should be considered as a cause or contributing factor in the differential diagnosis of conjunctival-corneal melt.
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