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Vertical transmission in chikungunya infection
M P Senanayake1, S M Senanayake, K K Vidanage
1Department of Paediatrics, Faculty of Medicine, University of Colombo, Sri Lanka. paed_colombo@yahoo.com
The Ceylon Medical Journal
|August 13, 2009
Summary
Chikungunya infection during pregnancy can lead to vertical transmission and adverse pregnancy outcomes in infants. This study details clinical and laboratory findings in affected newborns.
Area of Science:
- Infectious Diseases
- Maternal-Fetal Medicine
- Virology
Background:
- Chikungunya virus (CHIKV) infection poses a significant threat during pregnancy.
- Vertical transmission of CHIKV from mother to infant is a documented concern.
- Limited data exists on the comprehensive clinical and laboratory profiles of infants born to mothers with chikungunya during gestation.
Purpose of the Study:
- To investigate the pregnancy outcomes in women infected with chikungunya virus during pregnancy.
- To document the clinical and laboratory findings in infants born following maternal chikungunya infection.
- To assess the risks and manifestations associated with vertical transmission of chikungunya.
Main Methods:
- Retrospective case series analysis.
- Review of clinical records and laboratory data of mothers and infants.
- Clinical examination and diagnostic testing of neonates born to chikungunya-infected mothers.
Main Results:
- Evidence of vertical transmission of chikungunya virus was observed.
- Some cases exhibited poor pregnancy outcomes, including adverse effects on the neonates.
- Clinical and laboratory findings in affected infants were documented, highlighting specific manifestations.
Conclusions:
- Maternal chikungunya infection during pregnancy can result in vertical transmission.
- Adverse pregnancy outcomes are associated with chikungunya infection in pregnant women.
- Further research is warranted to fully understand the long-term implications and management strategies for chikungunya in pregnancy.
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