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[Viral infections associated with intestinal invagination]
I Calicó1, J M Bertrán Sangués, R I Elcuaz Romano
1Servicio de Microbiología, Hospital Vall d'Hebron, Barcelona.
Enfermedades Infecciosas Y Microbiologia Clinica
|August 1, 1990
Summary
Adenovirus infections are significantly linked to pediatric intestinal invagination, unlike enteroviruses. Further research is needed to identify unknown viral causes of this condition.
Area of Science:
- Virology
- Pediatric Gastroenterology
Context:
- Intestinal invagination in children often lacks a clear cause, though associations with tumors, adenovirus, and Yersinia enterocolitica exist.
- Viral infections are suspected contributors to pediatric intestinal invagination, necessitating etiological investigations.
Purpose:
- To investigate the role of adenovirus and enterovirus infections in pediatric intestinal invagination.
- To compare the prevalence of these viral infections in children with and without intestinal invagination.
Summary:
- A study of 88 children with intestinal invagination found adenovirus in 21.59% and enteroviruses in 13.63% of cases.
- Adenovirus detection was significantly higher in children with intestinal invagination compared to controls (6.7%).
- Enterovirus detection showed a smaller but significant difference between cases (6.98%) and controls.
Impact:
- The findings highlight a strong statistical association between adenovirus infections and pediatric intestinal invagination.
- The study suggests adenovirus may play a significant role in the etiology of intestinal invagination.
- The limitations of viral culture methods for identifying all potential viral causes are acknowledged.