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Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
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Bone Disorders01:29

Bone Disorders

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Multiple Sclerosis l: Introduction

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Connective Tissue Cell Types

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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

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Published on: December 9, 2015

[Vitamin D deficiency].

Henrik Hey1, Anne Schmedes, Peer Horn

  • 1Medicinsk Afdeling, Sygehus Lillebaelt, Vejle, DK-7100 Vejle. Henrik.Hey@slb.regionsyddanmark.dk

Ugeskrift for Laeger
|August 13, 2009
PubMed
Summary
This summary is machine-generated.

Vitamin D is crucial for bone health, but current intake recommendations are too low. Achieving optimal vitamin D levels (25-hydroxyvitamin D > 80 nmol/l) may require higher daily intake than currently advised.

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Methodology for Studying Interactions of Vitamin A Membrane Receptors and Opsin Protein with their Ligands in Generating the Retinylidene Protein

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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Methodology for Studying Interactions of Vitamin A Membrane Receptors and Opsin Protein with their Ligands in Generating the Retinylidene Protein
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Methodology for Studying Interactions of Vitamin A Membrane Receptors and Opsin Protein with their Ligands in Generating the Retinylidene Protein

Published on: October 4, 2024

Area of Science:

  • Endocrinology
  • Nutritional Science
  • Gerontology

Background:

  • Vitamin D's role in preventing osteoporosis and fractures is well-established for over 40 years.
  • Vitamin D deficiency is diagnosed by 25-hydroxyvitamin D (25-OHD) levels, with a target of > 50 nmol/l year-round.
  • Emerging research indicates potential prevention of severe diseases by elevating 25-OHD levels to 80 nmol/l.

Purpose of the Study:

  • To evaluate current vitamin D intake recommendations in light of new research suggesting higher optimal levels.
  • To determine the necessary daily vitamin D intake to achieve target 25-OHD concentrations of > 80 nmol/l.
  • To provide interim recommendations for vitamin D intake until higher doses are fully validated.

Main Methods:

  • Analysis of existing research on vitamin D metabolism and requirements.
  • Estimation of daily vitamin D intake needed to reach target serum concentrations.
  • Review of current public health recommendations for vitamin D intake.

Main Results:

  • Current vitamin D intake recommendations are insufficient to maintain 25-OHD levels > 50 nmol/l.
  • Estimated daily intake of 50-70 micrograms of vitamin D is required for individuals aged 10+ to reach 25-OHD levels > 80 nmol/l.
  • A provisional recommendation of 35-38 micrograms/day is suggested pending further safety documentation.

Conclusions:

  • Existing vitamin D guidelines require reassessment to ensure adequate levels for bone health and potential disease prevention.
  • Higher daily vitamin D intake is likely necessary to achieve optimal 25-OHD concentrations.
  • A cautious, evidence-based approach is needed for updating vitamin D recommendations.