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Related Experiment Video

Updated: Jun 21, 2026

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

Published on: March 6, 2019

Bioconjugates: harnessing potential for effective therapeutics.

Piush Khare¹, Aviral Jain, Arvind Gulbake

¹Pharmaceutics Research Projects Laboratory, Department of Pharmaceutical Sciences, Dr. Hari Singh Gour Vishwavidyalaya, Sagar (MP) 470 003, India.

Critical Reviews in Therapeutic Drug Carrier Systems

|August 14, 2009

Summary

Bioconjugation enables targeted drug delivery, directing therapeutic action specifically to diseased tissues. This minimizes side effects, enhancing treatment safety and efficacy for various conditions.

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Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

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Published on: March 8, 2018

Area of Science:

Bioconjugation chemistry
Drug delivery systems
Nanomedicine

Background:

Selective drug delivery is crucial for minimizing off-target side effects.
Bioconjugation offers a promising approach to achieve targeted therapeutic action.

Purpose of the Study:

To review the science of bioconjugation and its applications in drug delivery.
To explore different types of bioconjugates and their therapeutic strategies.
To highlight the utility of bioconjugates in treating major diseases like cancer.

Main Methods:

Review of existing literature on bioconjugation techniques.
Classification of bioconjugates into polymer-based, macromolecule-based, carrier-based, and novel types.
Discussion of experimental research and therapeutic strategies utilizing bioconjugates.

Main Results:

Bioconjugation facilitates precise drug targeting to diseased organs.
Various bioconjugate classifications demonstrate broad applicability in therapy.
Significant research supports the use of bioconjugates in cancer and other diseases.

Conclusions:

Bioconjugation represents a powerful tool for advancing drug delivery.
It holds immense potential for developing safer and more effective therapies.
This review serves as a reference for drug delivery and research professionals.