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Updated: Jun 21, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
[Newly acquired right bundle branch block. Association with heart disease and risk factors in the Reykjavik Study.]
Purpose:
To find risk factors for the appearance of right bundle branch block (RBBB) and to assess the prognosis of people with it.
Methods:
Subjects were participants in the Reykjavik Study who had acquired RBBB following an examination in a previous stage in this prospective population study, carried out in five stages in 1967-1991. Cases with two matched controls were recruited for a special examination in 1992.
Results:
Acquired RBBB was seen in 33 men and 14 women. Multivariate analysis showed, compared to the total population, that men with RBBB more often had cardiomegaly (odds ratio=OR 1.7;confidence limit=CL 1.2-2.5) women more often took antihypertensive drugs (OR 2.5; CL 1.5-4.1) and had lower diastolic blood pressure (OR 0.97; CL 0.95-0.99). Predictive factors in people with acquired RBBB were age (men: relative risk=RR 1.08; CL 1.05-1.11, women: RR 1.09; CL 1.02-1.17) and antihypertensive medication in women (RR 3.5; CL 1.2-10.4). There was no significant difference between cases and controls regarding examination, echocardiography and mortality.
Conclusion:
Factors associated with the appearance of RBBB are mainly age, cardiomegaly and antihypertensive medication.
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