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Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump
Published on: March 11, 2017
Flow injection determination of ketotifen fumarate using PVC membrane selective electrodes
M M Khater1, Y M Issa, Sabrein H Mohammed
1Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt.
Abstract:
In this study a PVC membrane electrode for determination of ketotifen fumarate is reported, where ketotifen tetraphenylborate (Keto-TPB) was used as ion exchanger. The electrode has linear range of 5.6x10(-6)-1.0x10(-2) and 1.0x10(-5)-1.0x10(-2) mol/L, with detection limits 2.37x10(-6)and 4.60x10(-6) mol/L in batch and flow injection analysis (FIA), respectively. The electrodes show a Nernstian slope value (58.40 and 61.50 mV/decade in batch and FIA, respectively), and the response time is very short (
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