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Related Concept Videos

Archival Research01:40

Archival Research

Some researchers gain access to large amounts of data without interacting with a single research participant. Instead, they use existing records to answer various research questions. This type of research approach is known as archival research. Archival research relies on looking at past records or data sets to look for interesting patterns or relationships. For example, a researcher might access the academic records of all individuals who enrolled in college within the past ten years and...
Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
Mismatch Repair01:20

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
Patch Clamp01:18

Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
Mortar Joint Deterioration in Masonry01:13

Mortar Joint Deterioration in Masonry

Mortar joint deterioration is a significant concern in masonry structures, with water accumulation in the joints leading to damage from freeze-thaw cycles. The repeated expansion of water during freezing and its melting during thawing develop and propagate cracks in the masonry joints. Eventually, this leads to the spalling of mortar from the joints, loosening masonry units and weakening the structure. The deteriorated mortar joints are also vulnerable to moisture intrusion into the walls.
The...
Cochran's Q Test01:17

Cochran's Q Test

Cochran's Q Test is a nonparametric statistical test used to determine if there are potential differences in the outcomes of three or more related groups on a binary (yes/no) or dichotomous outcome. It is essentially an extension of the McNemar Test, which is limited to two related samples - Cochran's Q test can handle three or more related samples, making it more versatile in scenarios where subjects are measured under multiple conditions. The test statistic follows a Chi-Square distribution,...

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Related Experiment Video

Updated: Jun 20, 2026

Kinematic History of a Salient-recess Junction Explored through a Combined Approach of Field Data and Analog Sandbox Modeling
06:55

Kinematic History of a Salient-recess Junction Explored through a Combined Approach of Field Data and Analog Sandbox Modeling

Published on: August 5, 2016

[Patch testing: historical aspects].

J-M Lachapelle1

  • 1Service de dermatologie, université catholique de Louvain, 30, Clos Chapelle-aux-Champs, UCL3033, 1200 Bruxelles, Belgique. Jean-marie.Lachapelle@uclouvain.be

Annales De Dermatologie Et De Venereologie
|August 19, 2009
PubMed
Summary
This summary is machine-generated.

This review covers over a century of patch testing history, beginning in 1895. It highlights the significant impact of French dermatological research and the establishment of GERDA.

Related Experiment Videos

Last Updated: Jun 20, 2026

Kinematic History of a Salient-recess Junction Explored through a Combined Approach of Field Data and Analog Sandbox Modeling
06:55

Kinematic History of a Salient-recess Junction Explored through a Combined Approach of Field Data and Analog Sandbox Modeling

Published on: August 5, 2016

Area of Science:

  • Dermatology
  • Allergology
  • Medical History

Context:

  • Patch testing, a diagnostic method for allergic contact dermatitis, has evolved significantly over more than 100 years.
  • The historical development of patch testing is crucial for understanding current dermatological practices.
  • The French dermatological community has played a pivotal role in advancing patch testing techniques and research.

Purpose:

  • To provide a comprehensive historical overview of patch testing.
  • To acknowledge and detail the contributions of French schools to the field of dermato-allergology.
  • To trace the origins and development of the Groupe d'études et de recherches en dermato-allergologie (GERDA).

Summary:

  • The history of patch testing dates back to J. Jadassohn's initial description in 1895.
  • The evolution of patch testing spans over a century, involving numerous advancements and refinements.
  • French contributions have been instrumental, leading to the formation of key research groups like GERDA.

Impact:

  • Understanding the history of patch testing provides context for its current applications and limitations.
  • Recognizing historical contributions can inspire future research and innovation in diagnosing skin allergies.
  • The establishment of GERDA signifies a structured approach to advancing research in dermato-allergology.