Progression of clinically stable lymphedema on lymphoscintigraphy

Lymphedema is due to dysfunction in lymphatic transport, and is divided into primary and secondary subtypes. Primary lymphedema is a congenital lymphatic abnormality or dysfunction whereas secondary lymphedema is characterized by pathologic disruption or obstruction of a previously-normal lymphatic system. The stage of lymphedema is determined clinically. Lymphoscintigraphy, however, may be used to assess disease extent, for early detection of disease progression, and can be used to direct therapy. We report a case of a 56-year-old woman with clinically stable lymphedema of 5 years, yet with lymphoscintigraphy findings compatible with disease progression.