Related Experiment Video
Updated: Jun 20, 2026

Time-Lapse Epifluorescence Microscopy Imaging of Pseudomonas aeruginosa and Staphylococcus aureus Heterogeneous Phenotypes
Published on: February 14, 2025
[Role of persistence characteristics of microorganisms in pathogenesis of endogenous infections]
Abstract:
Definition of endogenous bacterial infections (EBI) is formulated as well as their nosological variability is demonstrated and clinical and microbiological characteristics are characterized. Universal scheme of pathogenesis of these infections with separation of key phases of their course: premorbid phase, colonization, alteration, sanation or persistence. Important role of persistence characteristics of microorganisms for the development of EBI, which provide survival of agents during contacts with humoral and cellular effectors of host's immunity, is substantiated.
Related Concept Videos
Colonisation of Pathogens
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Microbial Interactions: Parasitism
Determinants of Bacterial Pathogenicity and Virulence
Fungal Phylum Microsporidia

