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Updated: Jun 20, 2026

Retropinacol/Cross-pinacol Coupling Reactions - A Catalytic Access to 1,2-Unsymmetrical Diols
10:12

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Published on: April 4, 2014

A new cross-coupling-based synthesis of carpanone

Frédéric Liron1, Francesco Fontana, Jean-Olivier Zirimwabagabo

  • 1Institut Parisien de Chimie Moléculaire UMR CNRS 7201, FR2769 Institut de Chimie Moléculaire, UPMC Univ Paris 06, Place Jussieu, 75005, Boite 183, Paris, France.

Organic Letters
|September 4, 2009
PubMed
Summary

Researchers developed a stereoselective synthesis for carpanone using a Suzuki-Miyaura coupling and Pd(II)-catalyzed oxidative coupling. This efficient six-step process yields a single diastereoisomer, proposing a novel reaction mechanism.

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