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Updated: Jun 20, 2026

Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry
Published on: September 3, 2010
Laser-enhanced electron-impact ionization spectroscopy
Abstract:
Sequential photon-excitation, electron-impact ionization with subsequent mass analysis has been applied to a barium atomic beam. High-resolution, Doppler-free laser excitation produces the 6s6p(1)P(1) excited state, which is then ionized by electron bombardment. The excited state is selectively ionized when bombardment energies are between the excited- and ground-state ionization thresholds. Mass discrimination has permitted the recording of individual optical spectra for all the stable isotopes, including the 0.1% abundant (130)Ba and (132)Ba, in a sample with natural isotopic abundances.
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