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Updated: Jun 20, 2026

Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
Published on: March 7, 2025
[Topical immune modulation and risk of cancer]
Mette Deleuran1, Claus Zachariae, Kristian Thestrup-Pedersen
1Dermatologisk Afdeling S, Arhus Universitetshospital, Arhus Sygehus, DK-8000 Arhus C. m.deleuran@dadlnet.dk
Abstract:
This article reviews if local immunosuppression of atopic dermatitis is associated with an increased risk of cancer - as implicated by a warning issued by the FDA and EMEA health authorities because systemic immunosuppression of transplanted patients leads to a significant increase of non-melanoma skin cancer and lymphoma. So far, no studies support that the use of topical immunosuppression increases the risk of local or systemic cancer.
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