Radiation techniques and toxicities for locally advanced breast cancer

Radiation therapy is used in the management of locally advanced breast cancer in the postmastectomy or neoadjuvant chemotherapy and breast-conservation setting to improve local-regional control and survival. Using modern-day technology, the therapeutic ratio has increased and the potential morbidity has decreased. This article reviews the technical aspects of radiation therapy for locally advanced breast cancer with emphasis on 3-dimensional radiotherapy techniques and discusses potential toxicities and how to reduce them.