Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 20, 2026

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach

Published on: May 23, 2025

Microvascular reconstructions after extensive soft tissue sarcoma resections in the upper limb.

I Barner-Rasmussen¹, P Popov, T Böhling

¹Department of Plastic Surgery, Töölö Hospital, Helsinki University Central Hospital, PO 266, 00029 HUS, Finland. ian.barner-rasmussen@helsinki.fi

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

|September 8, 2009

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Markers associated with genomic instability, immunogenicity and immune therapy responsiveness in Metaplastic carcinoma of the breast: Expression of γH2AX, pRPA2, P53, PD-L1 and tumor infiltrating lymphocytes in 76 cases.

BMC cancer·2022

Same author

Risk of coronary stenosis after adjuvant radiotherapy for breast cancer.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2022

Same author

Five-year follow-up results of aerobic and impact training on bone mineral density in early breast cancer patients.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2020

Same author

Craniomaxillofacial osteosarcoma - The role of surgical margins.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery·2019

Same author

Validation of the Finnish version of the BODY-Q patient-reported outcome instrument among patients who underwent abdominoplasty.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2019

Same author

Functional Outcome After Lower Extremity Soft Tissue Sarcoma Treatment: A Pilot Study Based on Translated and Culturally Adapted Measures.

Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society·2018

Microvascular reconstruction with free flaps is a reliable method for limb salvage in patients with upper extremity soft tissue sarcomas (STS). This approach offers acceptable oncological outcomes and functional results, making limb preservation possible.

Area of Science:

Oncology
Plastic Surgery
Orthopedic Oncology

Background:

Limb-sparing surgery and radiotherapy (RT) are standard treatments for extremity soft tissue sarcomas (STS).
Extensive tumor resections in the upper extremity can necessitate complex reconstructive techniques.

Purpose of the Study:

To evaluate the outcomes of microvascular reconstruction following extensive tumor resections in upper extremity soft tissue sarcomas.
To assess the efficacy and safety of free flap reconstruction in this patient population.

Main Methods:

Retrospective evaluation of 20 patients with upper extremity STS who underwent excision and microvascular reconstruction.
Radiotherapy was administered based on surgical margin status (<25 mm).
Outcomes assessed included flap survival, complications, oncological recurrence, survival rates, and functional limb outcomes.

More Related Videos

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation

Published on: June 13, 2025

Orthotopic Hind Limb Transplantation in the Mouse

Orthotopic Hind Limb Transplantation in the Mouse

Published on: February 12, 2016

Related Experiment Videos

Last Updated: Jun 20, 2026

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach

Vascularized Composite Hand Allograft Procurement and Preparation for Distal and Proximal Forearm Allotransplantation: A Stepwise Approach

Published on: May 23, 2025

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation

Published on: June 13, 2025

Orthotopic Hind Limb Transplantation in the Mouse

Orthotopic Hind Limb Transplantation in the Mouse

Published on: February 12, 2016

Main Results:

All 20 free flaps were successful, with no flap loss or operative mortality.
The wound complication rate was 15%, with a median follow-up of 74 months.
Five-year survival rates: 57% local recurrence-free, 67% metastasis-free, 45% disease-free, and 80% disease-specific overall survival.
94% limb salvage rate was achieved in patients treated with curative intent.

Conclusions:

Free flaps are a valuable and dependable option for reconstructing defects after extensive tumor resection in upper extremity STS.
Microvascular reconstruction is crucial for achieving limb salvage in these complex cases.
The oncological results are comparable to other extremity STS cases, and functional outcomes for the upper extremity are acceptable.