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[Benzodiazepines: patterns of use, tolerance and dependence]
M A Bernik1, M B Soares, C N Soares
1Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicinada Universidade de São Paulo, Brasil.
Arquivos De Neuro-Psiquiatria
|March 1, 1990
Abstract:
The authors review recent studies on benzodiazepine, the most largely used drug for insomnia and anxiety. In this paper are summarized: the development, patterns of use and abuse, mechanism of action, development of differential tolerance to its many effects, and the phenomena of withdrawal and dependence on the benzodiazepines.