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Updated: Jun 20, 2026
06:51
A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Multiple congenital plaquelike glomuvenous malformations with type 2 segmental involvement
Matthew A Hazey1, Anthony J Van Norman, Roxann L Powers
1Department of Medicine, West Virginia University School of Medicine, Morgantown, USA. mahazey@hsc.wvu.edu
Cutis
|September 12, 2009
Summary
Multiple congenital glomuvenous malformations (GVMs) are rare vascular anomalies. This case highlights a rare plaquelike GVM variant following Blaschko lines, suggesting specific segmental involvement.
Area of Science:
- Vascular Malformations
- Dermatology
- Genetics
Background:
- Glomuvenous malformations (GVMs) are rare congenital vascular anomalies.
- Multiple congenital GVMs are exceptionally rare, with most cases presenting as the plaquelike variant.
Observation:
- This report details a unique case of multiple congenital plaquelike GVMs.
- The observed pattern was suggestive of type 2 segmental involvement.
- The distribution followed Blaschko lines, indicating a potential genetic mosaicism.
Findings:
- The patient presented with multiple congenital plaquelike GVMs.
- The GVMs exhibited a segmental distribution consistent with Blaschko lines.
- This presentation suggests a specific subtype of GVMs with potential genetic underpinnings.
Implications:
- This case expands the known spectrum of congenital glomuvenous malformations.
- Understanding Blaschko line patterns in GVMs may aid in diagnosis and management.
- Further research into the genetic basis of segmental GVMs is warranted.
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