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Published on: September 16, 2025
Analysis of actual corneal flap thickness and confounding factors between first and second operated eyes
Sheng-Yao Hsu1, Hsin-Yi Chen, Chin-Pin Chung
1Department of Ophthalmology, Buddhist Tzu Chi General Hospital and Institute of Medical Sciences, and the Department of Ophthalmology and Visual Science, Institute of Medicine, Tzu Chi University, No 707, Section 3, Chung Yang Road, Hualien, Taiwan.
Background And Objective:
To calculate the actual corneal flap thickness during laser in-situ keratomileusis.
Patients And Methods:
Fifty-four women and 26 men with refractive error were enrolled in the study. Flaps were created using a MK-2000 microkeratome (Nidek, Gamagori, Japan) with a 130-microm head. The comparisons between both operated eyes of a patient and the correlations between flap thickness and confounding factors were analyzed.
Results:
The average flap thicknesses were 134.0 + or - 16.5 and 112.3 + or - 14.4 microm in the first and second operated eye groups, respectively, and the data showed a significant difference between the two groups (P < .001). There were positive correlations between central corneal thickness and flap thickness (first group, P = .017; second group, P = .041).
Conclusion:
The flap thicknesses of the first operated eye group were thicker than those of the second operated eye group and there was a positive correlation between the flap thickness and central corneal thickness. The coefficient of variation of the flap thickness was greater in the second group than in the first group.
