Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Physiology of Taste01:24

The Physiology of Taste

The perception of a salty flavor is facilitated by sodium ions within the oral salivary fluid. Upon consumption of a salty substance, salt crystals disassemble, leading to the liberation of its constituents—Na+ and Cl- ions. These ions subsequently dissolve into the salivary fluid present in the oral cavity. The external environment of the gustatory cells experiences an elevation in Na+ concentration, thereby establishing a potent concentration gradient. This gradient propels the diffusion of...
Carbohydrate Absorption01:25

Carbohydrate Absorption

Carbohydrates are essential macronutrients that serve as the body's primary energy source. Their digestion begins in the mouth, where salivary amylase partially breaks down complex carbohydrates such as starch into smaller oligosaccharides. This mechanical and enzymatic activity prepares carbohydrates for further processing in the gastrointestinal tract.
After being swallowed, the partially digested carbohydrates mix with gastric secretions in the stomach. However, the acidic environment...
Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

Modified-Release Drug Delivery Systems: Stimuli-Activated

Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...
Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
G-Protein Gated Ion Channels01:21

G-Protein Gated Ion Channels

GPCRs are primarily responsible for our sense of smell, taste, and vision.  The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
Sensory organs,...
Spare Receptors01:30

Spare Receptors

Some receptors remain unoccupied even when an agonist produces a maximal response. Such empty ones are called spare receptors. In presence of spare receptors the maximum effect of an agonist drug is achieved with fewer than 100% of the receptors being occupied. To determine the presence of spare receptors, scientists often compare the concentration of the drug needed to produce 50% of the maximum effect (EC50) with the concentration of the drug needed to occupy 50% of the receptors (Kd). If the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oppositely Charged Single Enzyme Nanogels Form Versatile Coacervates for Efficient Enzyme Cascade Catalysis.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Engineering a Transmembrane Receptor for Coacervate-Based Artificial Cells.

Journal of the American Chemical Society·2026
Same author

Converging frontiers in biomolecular condensate and synthetic cell research.

npj biomedical innovations·2026
Same author

Bio-Propelled Stomatocyte Nanomotors with Glutathione-Responsiveness for Osteoarthritis Treatment.

Angewandte Chemie (International ed. in English)·2026
Same author

Reconfiguration of Multiphase Coacervate Droplets Into Self-Regulated Nested Artificial Cells.

Angewandte Chemie (International ed. in English)·2026
Same author

Bottom-Up Coacervate-Based Artificial Cells: Integrating Cellular Hallmarks into Complex Life-Like Systems.

Angewandte Chemie (International ed. in English)·2026

Related Experiment Video

Updated: Jun 20, 2026

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
14:37

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles

Published on: July 6, 2012

Polymeric monosaccharide receptors responsive at neutral pH.

Kyoung Taek Kim1, Jeroen J L M Cornelissen, Roeland J M Nolte

  • 1Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, The Netherlands.

Journal of the American Chemical Society
|October 1, 2009
PubMed
Summary

Researchers synthesized Wulff-type styrenic monomers and polymerized them using RAFT. The resulting polymers show sugar-responsive solubilization in buffer solutions with monosaccharides like glucose.

More Related Videos

Automated Modular High Throughput Exopolysaccharide Screening Platform Coupled with Highly Sensitive Carbohydrate Fingerprint Analysis
12:02

Automated Modular High Throughput Exopolysaccharide Screening Platform Coupled with Highly Sensitive Carbohydrate Fingerprint Analysis

Published on: April 11, 2016

New Methods to Study Gustatory Coding
10:59

New Methods to Study Gustatory Coding

Published on: June 29, 2017

Related Experiment Videos

Last Updated: Jun 20, 2026

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles
14:37

High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles

Published on: July 6, 2012

Automated Modular High Throughput Exopolysaccharide Screening Platform Coupled with Highly Sensitive Carbohydrate Fingerprint Analysis
12:02

Automated Modular High Throughput Exopolysaccharide Screening Platform Coupled with Highly Sensitive Carbohydrate Fingerprint Analysis

Published on: April 11, 2016

New Methods to Study Gustatory Coding
10:59

New Methods to Study Gustatory Coding

Published on: June 29, 2017

Area of Science:

  • Polymer Chemistry
  • Organic Synthesis
  • Materials Science

Background:

  • Wulff-type monomers are crucial building blocks in polymer science.
  • Controlled polymerization techniques are essential for designing advanced materials.

Purpose of the Study:

  • To report the synthesis of novel Wulff-type styrenic monomers.
  • To investigate their polymerization using radical addition-fragmentation chain transfer (RAFT).
  • To evaluate the sugar-responsive properties of the synthesized polymers.

Main Methods:

  • Synthesis of Wulff-type styrenic monomers.
  • Radical addition-fragmentation chain transfer (RAFT) polymerization.
  • Characterization of polymers and block copolymers.
  • Solubilization studies in aqueous buffer solutions with monosaccharides.

Main Results:

  • Successful synthesis of Wulff-type styrenic monomers.
  • Controlled polymerization achieved via RAFT methods.
  • Polymers and block copolymers demonstrated sugar-responsive solubilization.
  • Solubilization observed in pH 7.4-7.8 buffer with D-fructose and D-glucose.

Conclusions:

  • Wulff-type styrenic monomers can be effectively synthesized and polymerized.
  • RAFT polymerization offers control over polymer architecture.
  • The developed polymers exhibit tunable, sugar-induced solubility for potential applications.