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Updated: Jun 19, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Successful non contrast percutaneous coronary intervention for patient with unstable angina and prior anaphylactic
Mamoru Sakakibara1, Hiroyuki Tsutsui
1Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo. mike.s@ninus.ocn.ne.jp
Insights
This study presents a successful coronary interventional procedure for a patient with severe coronary artery stenosis. The innovative technique utilized intravascular ultrasound and a marker wire, avoiding iodinated contrast media.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Imaging
Background:
- Patient history of angina, percutaneous coronary intervention, and coronary bypass surgery.
- Hospitalization for epigastralgia and tarry stool, indicating potential gastrointestinal bleeding.
- Previous uneventful percutaneous coronary intervention without allergic reaction to contrast media.
Observation:
- Hypotension and chest pain during enhanced computed tomography.
- Recurrent hypotension during coronary angiography (CAG).
- Significant coronary artery stenosis in the right coronary artery identified via CAG.
Findings:
- Successful coronary interventional procedure for severe coronary artery stenosis.
- Utilized intravascular ultrasound and a second wire as a marker for stent implantation.
- Achieved successful stent implantation without the use of iodinated contrast media.
Implications:
- Demonstrates a viable alternative for contrast-enhanced procedures in high-risk patients.
- Highlights the utility of intravascular ultrasound and marker wires in complex interventional cardiology.
- Offers a novel approach for managing patients with contraindications or severe reactions to contrast media.
Abstract:
A 53-year-old man, who had a history of angina treated by percutaneous coronary intervention without allergic reaction to contrast and coronary bypass surgery, was hospitalized due to epigastralgia and tarry stool. During an enhanced computed tomography for the evaluation of abdominal diseases, he became hypotensive and had chest pain. To diagnose acute coronary syndrome, coronary angiography (CAG) was performed after the intravenous administration of hydrocortisone. He became hypotensive again during the CAG, which revealed significant coronary artery stenosis in the right coronary artery. Despite the intensive medical treatment, he had angina even while walking in the ward. By using an intravascular ultrasound for coronary stent implantation and the second wire as a marker for the stent implantation, we performed coronary interventional procedures successfully for this patient without the use of iodinated contrast media.
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