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Total synthesis of the marine bromotyrosine alkaloid moloka'iakitamide

Makoto Yoshida1, Kentaro Yamaguchi

  • 1Faculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University, Sanuki, Kagawa769-2193, Japan.

Chemical & Pharmaceutical Bulletin
|October 6, 2009
PubMed

Abstract:

The first total synthesis of moloka'iakitamide (1), a recently reported bromotyrosine alkaloid from Pseudoceratina arabica with oxalamide moiety, was achieved in 7 steps from commercially available tyramine (26% overall).

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