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Updated: Jan 14, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Tuning rotational barriers through substituent modification in catechol-diyl molecular gyrotops

Hyu Kishii1, Yusuke Inagaki1, Kazuaki Ohara2

  • 1Division of Applied Chemistry, Faculty of Urban Environmental Sciences, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0397, Japan. wsetaka@tmu.ac.jp.

Organic & Biomolecular Chemistry
|October 17, 2025
PubMed
Abstract

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