[Primary thyroid lymphoma. Report of four cases]

Area of Science:

• Oncology
• Hematology
• Endocrinology

Background:

• Primary thyroid lymphoma is a rare malignancy, typically of the non-Hodgkin lymphoma subtype.
• Understanding its clinical presentation and treatment response is crucial for patient management.

Observation:

• This report details four female patients diagnosed with primary thyroid lymphoma.
• Patient ages ranged from 16 to 81 years.
• Clinical courses varied significantly among the cases.

Findings:

• One 16-year-old patient achieved disease-free status after surgery and chemotherapy.
• An 81-year-old patient received surgery and chemotherapy but was lost to follow-up.
• An 80-year-old patient died post-operatively from multiple organ failure.
• A 54-year-old patient, post-surgery, rejected chemotherapy and was lost to follow-up.

Implications:

• The diverse outcomes highlight the heterogeneous nature of primary thyroid lymphoma.
• Treatment adherence, including chemotherapy, appears critical for favorable prognoses.
• Further research into optimal management strategies for this rare condition is warranted.