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Related Concept Videos

Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
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Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Updated: Jun 19, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
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Pulmonary carcinosarcoma masquerading as a cryptic disseminated malignancy.

Amulyajit Kaur1, J J J Falleiro, A K Ghosh

  • 1Department of Pathology, Military Hospital Cardiothoracic Center, Pune Camp, Maharashtra 411040, India. amulyabhatti@rediffmail.com

Indian Journal of Pathology & Microbiology
|October 7, 2009
PubMed
Summary
This summary is machine-generated.

This case report details a rare, aggressive pulmonary carcinosarcoma with unusual clinical features. The advanced lung cancer metastasized to the heart, lymph nodes, and adrenals, presenting diagnostic challenges.

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Area of Science:

  • Oncology
  • Pathology

Background:

  • Pulmonary carcinosarcoma is a rare, aggressive lung malignancy.
  • It is characterized by a mixture of carcinoma and sarcoma components.

Observation:

  • A unique case presented with cryptic clinical features, diagnosed post-mortem as stage IV lung malignancy.
  • Histopathology revealed a carcinosarcoma composed of adenocarcinoma and osteosarcoma.

Findings:

  • The tumor metastasized to the heart, lymph nodes, and both adrenal glands.
  • This represents the first reported instance of this subtype with cardiac metastasis.

Implications:

  • This case highlights the diagnostic challenges posed by unusual presentations of pulmonary carcinosarcoma.
  • Understanding rare metastatic patterns is crucial for improving diagnosis and management of aggressive lung cancers.