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Updated: Jun 19, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
[Use of D-dimer to exclude upper extremity deep venous thrombosis]
Hans-Ulrik Ahler-Toftehøj1, Peter Mikkelsen
1Ortopaedkirurgisk Afdeling, Herlev Hospital, DK-2730 Herlev. hantof01@heh.regionh.dk
Abstract:
D-dimer is often used to exclude deep venous thrombosis, primarily in the lower extremities. We describe a 38-year-old man who had deep venous thrombosis in the left vena subclavia in spite of a normal D-dimer. Only one inconclusive survey compares the value of D-dimer and upper extremity deep venous thrombosis. We conclude that where deep venous thrombosis of the upper extremities is suspected, you cannot rely on the D-dimer value, but should examine the patient using other modalities such as colour Doppler ultrasound.
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