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08:01
Measurement of Insulin- and Contraction-Stimulated Glucose Uptake in Isolated and Incubated Mature Skeletal Muscle from Mice
Published on: May 16, 2021
Magnesium sulfate enhances exercise performance and manipulates dynamic changes in peripheral glucose utilization.
Shiu-Min Cheng1, Lin-Lan Yang, Sy-Huah Chen
1Department of Psychology, Asia University, Wufeng, Taichung, 413, Taiwan.
European Journal of Applied Physiology
|October 10, 2009
Summary
Magnesium sulfate supplementation significantly improved exercise duration and altered blood glucose metabolism in gerbils. This study suggests magnesium enhances athletic performance by increasing glucose and magnesium levels while reducing lactate during exercise.
Area of Science:
- Exercise Physiology
- Nutritional Biochemistry
- Sports Science
Background:
- The role of magnesium supplementation in exercise performance is debated.
- Understanding magnesium's impact on glucose metabolism during physical exertion is crucial for athletes.
Purpose of the Study:
- To investigate the effects of magnesium sulfate on exercise performance.
- To examine magnesium sulfate's influence on blood glucose and lactate metabolism during exercise.
Main Methods:
- Developed an auto-blood sampling system coupled with a microdialysis analyzer for continuous monitoring in freely moving gerbils.
- Gerbils were pretreated with magnesium sulfate (90 mg/kg) or saline before forced swimming exercise.
- Measured plasma glucose, lactate, and magnesium levels at basal and during exercise/recovery periods.
Main Results:
- Magnesium sulfate significantly increased forced swimming duration by 71% (p < 0.01).
- Magnesium sulfate elevated plasma glucose and magnesium levels (175% and 302% of basal, respectively) and reduced lactate levels (150% of basal) during exercise (p < 0.05).
- Plasma magnesium levels increased significantly during exercise and recovery in supplemented gerbils.
Conclusions:
- Magnesium sulfate enhances exercise performance, likely by improving glucose availability and lactate clearance.
- These findings support the potential benefits of magnesium supplementation for improving athletic performance.
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