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Activation of a novel medullary pathway elicits a vagal, cholinergic bronchoconstriction in guinea-pigs
J A Hey1, M del Prado, R W Chapman
1Department of Allergy and Inflammation, Schering-Plough Research, New Jersey 07003.
Pulmonary Pharmacology
|January 1, 1990
Abstract:
Electrical stimulation of structures within the rostral region of the dorsal medulla of the guinea-pig activates a vagal cholinergic bronchoconstriction pathway and simultaneously activates a sympathetic inhibitory input. Removal of the latter by spinal section potentiated CNS-induced bronchospasm.