Related Experiment Video
Updated: Jun 19, 2026
04:25
A Mice Model of Chlorhexidine Gluconate-Induced Peritoneal Damage
Published on: April 28, 2022
Encapsulating peritoneal sclerosis: importance to the hemodialysis practitioner
Jeffrey Perl1, Joanne M Bargman, Christopher T Chan
1Department of Nephrology, University Health Network, Toronto, Ontario, Canada.
Hemodialysis International. International Symposium on Home Hemodialysis
|October 21, 2009
Summary
Encapsulating peritoneal sclerosis (EPS) is a severe complication of peritoneal dialysis (PD). Early diagnosis and treatment, including immunosuppression and nutritional support, are crucial for managing this condition in hemodialysis patients.
Area of Science:
- Nephrology
- Gastroenterology
Background:
- Encapsulating peritoneal sclerosis (EPS) is a rare but serious complication of long-term peritoneal dialysis (PD).
- It involves peritoneal membrane inflammation, fibrosis, and intestinal encapsulation, leading to poor prognosis.
Observation:
- EPS diagnosis often occurs after transfer to hemodialysis (HD).
- Patients may present with ascites and recurrent small bowel obstruction.
Findings:
- Risk factors for EPS are not fully understood, but longer PD duration increases frequency.
- Early immunosuppressive therapy is key; parenteral nutrition and surgery may be needed for obstruction.
Implications:
- HD practitioners must maintain a high index of suspicion for EPS in patients with GI symptoms and prior PD history.
- Prompt diagnosis and treatment initiation are essential for improving outcomes in EPS patients.
Related Concept Videos
01:25Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
01:25Peritoneal Dialysis III: Nursing Management
Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
01:30Peritoneal Dialysis I: Introduction and Procedure
Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
01:30Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
01:25Hemodialysis I: Introduction
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
01:24Hemodialysis II: Procedure and Complications
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...