Autocorrelation evaluation from clipped photon detection
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Updated: Jun 19, 2026

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Confocal Microscopy Reveals Cell Surface Receptor Aggregation Through Image Correlation Spectroscopy
Published on: August 2, 2018
Optics Letters
|October 22, 2009
Abstract:
We present two new techniques for estimating the autocorrelation function, based on the measurement of the mean number of clipped photocounts and on the calculation of the second-order factorial moment of a series of clipped data. The first procedure has the advantage of simplicity, although it produces a poor signal-to-noise ratio. On the other hand, the second technique gives a very good signal-to-noise ratio, when compared with other known methods.
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