Wilms' tumor metastatic to the orbit.

Area of Science:

• Pediatric Oncology
• Ophthalmology
• Pathology

Background:

• Wilms' tumor is a common pediatric kidney cancer.
• Secondary invasion of ocular adnexa by Wilms' tumor is rare.
• Orbital masses in immunocompromised children can mimic infections.

Observation:

• A 2.5-year-old boy presented with a proptotic right lower lid.
• The patient had a history of primary abdominal Wilms' tumor treated with chemotherapy.
• Echography revealed a firm orbital mass with orbital floor destruction.

Findings:

• Biopsy confirmed metastatic Wilms' tumor cells in the orbital mass.
• The orbital mass was not an abscess or fungal infection.
• Wilms' tumor metastasis to the ocular adnexa was diagnosed.

Implications:

• This case highlights the potential for Wilms' tumor metastasis to the orbit.
• Early detection and biopsy are crucial for accurate diagnosis of orbital masses in pediatric cancer patients.
• Ocular adnexa invasion by Wilms' tumor necessitates tailored treatment strategies.