Related Experiment Videos
Ketorolac: an injectable NSAID
1Hahnemann University School of Medicine, Philadelphia, Pennsylvania.
American Family Physician
|January 1, 1991
Summary
Ketorolac tromethamine, a nonsteroidal anti-inflammatory drug, effectively manages acute pain and postoperative pain, offering an alternative to morphine without respiratory depression or abuse potential.
Area of Science:
- Pharmacology
- Pain Management
- Anesthesiology
Background:
- Ketorolac tromethamine is the first injectable NSAID for acute pain.
- Postoperative pain management often involves opioids like morphine.
Purpose of the Study:
- To evaluate ketorolac tromethamine's efficacy and safety in managing acute and postoperative pain.
- To compare ketorolac tromethamine with morphine for pain relief.
Main Methods:
- Clinical studies comparing ketorolac tromethamine to morphine.
- Assessment of analgesic potency and adverse effects.
Main Results:
- Ketorolac tromethamine demonstrates comparable analgesic potency to morphine for postoperative pain.
- Ketorolac offers advantages over morphine, including no respiratory depression and no abuse potential.
- Ketorolac has a longer duration of action and less central nervous system effect than morphine.
Conclusions:
- Ketorolac tromethamine is a viable option for acute and postoperative pain management.
- It provides effective pain relief with a favorable safety profile compared to opioids.
- Ketorolac tromethamine is not recommended for obstetric analgesia.