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Related Experiment Videos

Ketorolac: an injectable NSAID.

J R DiPalma1

  • 1Hahnemann University School of Medicine, Philadelphia, Pennsylvania.

American Family Physician
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Ketorolac tromethamine, a nonsteroidal anti-inflammatory drug, effectively manages acute pain and postoperative pain, offering an alternative to morphine without respiratory depression or abuse potential.

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Area of Science:

  • Pharmacology
  • Pain Management
  • Anesthesiology

Background:

  • Ketorolac tromethamine is the first injectable NSAID for acute pain.
  • Postoperative pain management often involves opioids like morphine.

Purpose of the Study:

  • To evaluate ketorolac tromethamine's efficacy and safety in managing acute and postoperative pain.
  • To compare ketorolac tromethamine with morphine for pain relief.

Main Methods:

  • Clinical studies comparing ketorolac tromethamine to morphine.
  • Assessment of analgesic potency and adverse effects.

Main Results:

  • Ketorolac tromethamine demonstrates comparable analgesic potency to morphine for postoperative pain.

Related Experiment Videos

  • Ketorolac offers advantages over morphine, including no respiratory depression and no abuse potential.
  • Ketorolac has a longer duration of action and less central nervous system effect than morphine.

    • Conclusions:

    • Ketorolac tromethamine is a viable option for acute and postoperative pain management.
    • It provides effective pain relief with a favorable safety profile compared to opioids.
    • Ketorolac tromethamine is not recommended for obstetric analgesia.