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Familial multiple desmoplastic trichoepitheliomas.

P E Shapiro1, A W Kopf

  • 1Department of Dermatology, Yale University School of Medicine, New Haven, Conn. 06510.

Archives of Dermatology
|January 1, 1991
PubMed
Summary
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Multiple desmoplastic trichoepitheliomas in a family suggest an inherited condition. This finding impacts the classification and treatment of these skin tumors.

Area of Science:

  • Dermatology
  • Genetics
  • Oncology

Background:

  • Desmoplastic trichoepitheliomas are benign skin tumors.
  • Familial occurrence of multiple lesions is rare.

Observation:

  • A kindred with multiple desmoplastic trichoepitheliomas was studied.
  • The affected individuals presented with numerous primary tumors.

Findings:

  • Multiple desmoplastic trichoepitheliomas indicate a potential inherited genetic pattern.
  • This presentation suggests a hereditary basis for the condition.

Implications:

  • Desmoplastic trichoepitheliomas should be recognized as a marker for inherited disorders.
  • Classification and treatment strategies for these tumors may need revision.

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  • Further research into the genetic underpinnings is warranted.